Osmosis Jones

Plot

A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

About Osmosis Jones

Osmosis Jones is a 2001 American live-action/animated buddy cop action comedy film directed by the Farrelly brothers (Peter and Bobby Farrelly) and written by Marc Hyman starring the voices of Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood and William Shatner, with Molly Shannon, Chris Elliott and Bill Murray in live-action roles. It combines live-action sequences directed by the Farrelly Brothers and animated ones directed by Piet Kroon and Tom Sito and follows the titular protagonist, an anthropomorphic white blood cell police officer (Rock), as he teams up with a cold pill (Pierce) to protect his unhealthy human host (Murray) from a deadly virus (Fishburne) he unintentionally contracted. Filming for the live-action sequences took place in Plymouth, Massachusetts from April 2, 2000 to June 19, 2000. Although originally expected to be released in November 2000, it premiered on August 7, 2001 and was theatrically released three days later by Warner Bros. Pictures. It received mixed reviews from critics, who praised the worldbuilding, animation, story, and voice performances, but criticized the inconsistent tone of the live-action portions and overuse of gross-out humor. The film was also a commercial failure, grossing $14 million worldwide against a $70 million budget. Despite the poor financial response, the film garnered success on home video, followed by…

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